Question 1 (10pts)
a) What is chance of observing 61325 when rolling open dice?
Probabilities control open dice: P(1)=P(2)=P(3)=P(4)=P(5)=P(6)=1/6
b) What is chance of observing 61325 when rolling loaded dice?
Probabilities control open dice: P(1)=P(2)=P(3)=P(4)=P(5)= 0.1 and P(6)=0.5
Question 2 (50pts). On a granted island poison ebullition becomes a intimidation of advenient pandemic. Researchers feel narrowed down the inducement of ebullition to span poisones (poison 1 and poison 2). The DNA sequencing lab receives a scantling control elevate separation. Unfortunately, the scantling was profligate and the dissolution of controleign DNA leaves the lab with a soon DNA fragment: AGTAGCTTCCAG. Given perfect serviceable counsel (granted subordinateneath) how can lab individualize the emblem of the poison that inducementd the ebullition.
Nucleotide probabilities of poison1
P(G)=P(C) = 0.2
Nucleotide probabilities of poison 2
– Poison 1 and Poison 2 are equivalent slight to betide in regularity.
– nucleotides are rebellious and identically as sorted.
Question 3 (40 pts)
Align span sequences shown subordinateneath using Needelman Wunsch algorithm.
Use contest account of 4, miscontest account of -4 and derangement pain account of -2.
a) dynamic programming matrix with accounts (as it shown in Figure 6.1, Ewens or in Figure 2.5, Durbin which is serviceable subordinate Course Content.)
b) track tail pointers
c) alignment account
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