Bio – patient scenario (upstream/downstream) assignment





Unrepining Scenario (Upstream/Downstream) Enactment




Addresses Learning Outcomes:




  • Reason conversance of bioclose principles and the Or-laws System to ask and counter-argument appropriate inquirys encircling cosmical bloom and sickness
  • Analyze instruction to divide betwixt sick and bloomy building and exerciseing.
  • Analyze how interior and manifest factors principle a-breaking-up of bloomy whole exercise, qualitative to sickness and disorders.








Mr. Smith is 60 years aged. He was diagnosed with prostate cancer five years gone-by. Over the gone-by rare days, Mr. Smith has been consciousness increasingly wearied and has also been trouble from a excess that did referable attribuconsultation attribuconsultation attribuconsultation meet to over-the-counter medications. He scheduled an enactment with his physician.




His physician manufactured a tangible criterion and recommended a battery of laboratory experiments and imaging procedures.




His race urgency is 165/100 mmHg.  MRI reveals metastasis of prostate cancer to osseous construction. Abdominal CT pretences hinderance of interior impuconsultation to nodular extension of adrenal glands.




The table below pretences Intimation values in the right-hand post. These values contemplate the regular order of values ce unrepinings externally sickness or illness.  The character post contemplates the resulting values ce medical experiment results obtained ce Mr. Smith.




Choose referable attribuconsultation attributablee whether Mr. Smith’s values are among regular limits.




Laboratory results from Mr. Smith’s avoid hospital path and medical experiments pretence subjoined findings: 





Mr. Smith

Intimation Values


2.6 mmol/L



7.3 g/dl

13.8 to 18.2 g/dL




Platelet Count




38 mmol/l

22-26 mmol/L

Urinary K+

70 mmol/L/24 hr

25-120 mmol/L/24 hr

Race Glucose

460 mg/dl

64.8-104.4 mg/dL

Serum Aldosterone

1 ng/dl

 <31 ng/dL

24 hour Urinary Aldosterone

8.4 mcg/24 hr

2.3-21.0 mcg/24 hr


2.1 ng/ml/hr

0.65-5.0 ng/ml/hr

ACTH (Adrenocorticotropic Hormone)

1082 pg/ml

9-46 pg/ml


155.5 microg/dL

0-25 microg/dL












Laboratory findings, MRI and CT aged metastatic prostate adenocarcinoma, hypertension and contumacious hypokalemia impuconsultation to ectopic ACTH cemation. High levels of circulating cortisol principled consecutive activation of mineralocorticoid receptors resulting in hypokalemia, metabolic alkalosis and hypertension.








After balbutiation supposing scenario, counter-argument the subjoined inquirys:




1.  1.What are the factors of tangible criterion? Describe each factor. (See Module 1, Culminationic 8, Part B.2)




2.  2.Mr. Smith’s race urgency was 160/100 mmHg.




a. How does a medical provider choose or estimate race urgency?




b.  What do the culmination (numerator) and ground (denominator) mass moderation in the bioclose soundness?




c.  What is the reason the dimension of these brace mass?




d.  Is Mr. Smith’s race urgency among regular order? Explain how you concluded whether Mr. Smith’s race urgency is/is referable attribuconsultation attribuconsultation attribuconsultation among regular order.




e.  Sift-canvass the potential bloom issues anticipated ce a special with a race urgency of 165/100 mm Hg.




3.   3.Grounded on the grounds supposing, what laboratory experiments were manufactured and what samples were choosen from the unrepining?  Select single of the laboratory experiments ordered ce Mr. Smith and sift-canvass why Mr. Smith’s physician faculty feel ordered the experiment and the instruction she faculty feel expected to obtain from that detail experiment.




4.   4. Analyze Mr. Smith’s values




 a.Collate Mr. Smith’s values with intimation values and manifest whether Mr. Smith’s values are below, aloft, or among regular order (collate Mr. Smith’s values with the Intimation values) ce each laboratory experiments in the consultation aloft from the avoid be of experiments. 




b. Select single of the values without of regular order from the consultation aloft and sift-canvass potential medical concerns everyied to the verified alter in Mr. Smith’s values.




5.  5.  What imaging procedures did Mr. Smith rafter? Sift-canvass the distinctions and similarities betwixt the brace incongruous imaging approaches. What were the results of imaging procedures in Mr. Smith’s plight?




6. Select single of the medical provisions from the CONCLUSION and DIAGNOSIS minority aloft and limit what it moderations.  Also, sift-canvass, in your admit tone and grounded on what you can gather encircling Mr. Smith’s mode, how the laboratory or imaging experiments helped with contemplation a blank or making the singularity. In your admit tone, sift-canvass how medical providers reason the or-laws system to purpose to exertion through the criterion and singularity of a unrepining.




You should transcribe a less essay addressing every five inquirys and refer it below “Assignments”. Your action conquer await upon the contented, clarity and formerity of responses written in your admit tone. Good letter practices, including the reason of empurpose rhetoric, passage and section building, and punctuation, and intercourse of close forced, conquer recital ce a participation of your action.




Cite every sources in APA cemat among your counter-argument citation as well-mannered-mannered as unmeasured citations in APA cemat at the purpose of the enactment.




Your action ce the less essay grounded on presented scenario conquer be grounded on the subjoined factors:




  1. Answered every six inquirys and every sub-parts of each inquiry and provides empurpose or close counter-arguments to each inquiry—up to 60 points
  2. Student provides former, specific responses, written in student’s admit tone, pretenceing intercourse of close forced – up to 24 points
  3. Student incorporates provisions and concepts scholarly from assigned materials – up to 8 points
  4. Student emendly cites media in APA cemat – up to 4 points
  5. Form – rhetoric, spelling, title – up to 4 points






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